Performance Statistics of Defined Approaches for Eye Hazard Identification of Non-Surfactant Liquids to Distinguish between the Three United Nations Globally Harmonized System Categories

Performance Statistics of Defined Approaches for Eye Hazard Identification of Non-Surfactant Liquids to Distinguish between the Three United Nations Globally Harmonized System Categories

Introduction: Cosmetics Europe develops two defined approaches (DAs) for eye hazard identification, that is, addressing serious eye damage (Cat. 1), eye irritation (Cat. 2), and the absence thereof (No Cat.), for nonsurfactant liquid test substances. DAL-1 combines four physicochemical properties, t...

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Bibliographic Details
Main Authors: Abo, T. (Author), Adriaens, E. (Author), Alépée, N. (Author), Bagley, D. (Author), Mewes, K.R (Author)
Format: Article
Language:English
Published: Mary Ann Liebert Inc. 2021
Subjects:
Article
cell viability
controlled study
cornea opacity
corrosion
defined approach
diagnostic test accuracy study
Draize eye test
ester
eye disease
eye irritation
eye irritation test
hazard
human
human cell
in vitro test methods
liquid
non surfactant liquid
OECD
phototoxicity
physical chemistry
physicochemical properties
prediction
quantitative structure activity relation
sensitivity and specificity
serious eye damage and eye irritation
skin irritation
statistics
surface tension
UN GHS
United Nations
visual system examination
water solubility
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