Association between opioid dose escalation and time to death in a comfort measures only population

Association between opioid dose escalation and time to death in a comfort measures only population

Purpose: Opioids are crucial to the relief of pain and dyspnea experienced by patients dying in the hospital setting; however, there are concerns about the association of opioid dosage with hastened death via opioid-induced respiratory depression, and there is little published evidence regarding the...

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Bibliographic Details
Main Authors: Abraham, D.L (Author), Ayers, G.T (Author), Hernandez, I. (Author), Pruskowski, J.A (Author)
Format: Article
Language:English
Published: Oxford University Press 2021
Subjects:
adult
Adult
aged
Aged
Analgesics, Opioid
Article
Charlson Comorbidity Index
cohort analysis
Cohort Studies
comfort measures only order
consultation
controlled study
death
drug dose escalation
drug megadose
electronic health record
end-of-life care
female
Female
human
Humans
kidney function
liver function
major clinical study
male
Male
medical record
multicenter study
narcotic analgesic agent
opiate
opioid
pain
Pain
pain management
palliative care
Palliative Care
palliative therapy
priority journal
proportional hazards model
Retrospective Studies
retrospective study
survival time
terminal care
time of death
traumatic brain injury
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