Founder reconstruction enables scalable and seamless pangenomic analysis

Motivation: Variant calling workflows that utilize a single reference sequence are the de facto standard elementary genomic analysis routine for resequencing projects. Various ways to enhance the reference with pangenomic information have been proposed, but scalability combined with seamless integra...

Full description

Bibliographic Details
Main Authors: Cazaux, B. (Author), Dönges, S. (Author), Mäkinen, V. (Author), Norri, T. (Author), Valenzuela, D. (Author)
Format: Article
Language:English
Published: Oxford University Press 2021
Online Access:View Fulltext in Publisher