Computing optimal factories in metabolic networks with negative regulation

MOTIVATION: A factory in a metabolic network specifies how to produce target molecules from source compounds through biochemical reactions, properly accounting for reaction stoichiometry to conserve or not deplete intermediate metabolites. While finding factories is a fundamental problem in systems...

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Bibliographic Details
Main Authors: Kececioglu, J. (Author), Krieger, S. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Online Access:View Fulltext in Publisher