From drug repositioning to target repositioning: prediction of therapeutic targets using genetically perturbed transcriptomic signatures
MOTIVATION: A critical element of drug development is the identification of therapeutic targets for diseases. However, the depletion of therapeutic targets is a serious problem. RESULTS: In this study, we propose the novel concept of target repositioning, an extension of the concept of drug repositi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
NLM (Medline)
2022
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| Online Access: | View Fulltext in Publisher |