MeConcord: a new metric to quantitatively characterize DNA methylation heterogeneity across reads and CpG sites

MOTIVATION: Intermediately methylated regions occupy a significant fraction of the human genome and are closely associated with epigenetic regulations or cell-type deconvolution of bulk data. However, these regions show distinct methylation patterns, corresponding to different biological mechanisms....

Full description

Bibliographic Details
Main Authors: Wang, X. (Author), Zhang, X. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Online Access:View Fulltext in Publisher