MeConcord: a new metric to quantitatively characterize DNA methylation heterogeneity across reads and CpG sites
MOTIVATION: Intermediately methylated regions occupy a significant fraction of the human genome and are closely associated with epigenetic regulations or cell-type deconvolution of bulk data. However, these regions show distinct methylation patterns, corresponding to different biological mechanisms....
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
NLM (Medline)
2022
|
Online Access: | View Fulltext in Publisher |