twas_sim, a Python-based tool for simulation and power analysis of transcriptome-wide association analysis

SUMMARY: Genome-wide association studies (GWASs) have identified numerous genetic variants associated with complex disease risk; however, most of these associations are non-coding, complicating identifying their proximal target gene. Transcriptome-wide association studies (TWASs) have been proposed...

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Bibliographic Details
Main Authors: Bhattacharya, A. (Author), Lu, Z. (Author), Mancuso, N. (Author), Pasaniuc, B. (Author), Wang, X. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2023
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