Primary cilia control endothelial permeability by regulating expression and location of junction proteins
Aims: Wall shear stress (WSS) determines intracranial aneurysm (IA) development. Polycystic kidney disease (PKD) patients have a high IA incidence and risk of rupture. Dysfunction/absence of primary cilia in PKD endothelial cells (ECs) may impair mechano-transduction of WSS and favour vascular disor...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |