Primary cilia control endothelial permeability by regulating expression and location of junction proteins

Primary cilia control endothelial permeability by regulating expression and location of junction proteins

Aims: Wall shear stress (WSS) determines intracranial aneurysm (IA) development. Polycystic kidney disease (PKD) patients have a high IA incidence and risk of rupture. Dysfunction/absence of primary cilia in PKD endothelial cells (ECs) may impair mechano-transduction of WSS and favour vascular disor...

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Bibliographic Details
Main Authors: Allémann, E. (Author), Bijlenga, P. (Author), Cayron, A.F (Author), Diagbouga, M.R (Author), Georges, M. (Author), Haemmerli, J. (Author), Hierck, B.P (Author), Kwak, B.R (Author), Lemeille, S. (Author), Morel, S. (Author)
Format: Article
Language:English
Published: Oxford University Press 2022
Subjects:
Endothelial permeability
Intercellular junctions
Intracranial aneurysm
Primary cilium
Wall shear stress
Online Access:View Fulltext in Publisher

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