A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells

Chinese hamster ovary (CHO) cells are widely used for producing biopharmaceuticals, and engineering gene expression in CHO is key to improving drug quality and affordability. However, engineering gene expression or activating silent genes requires accurate annotation of the underlying regulatory ele...

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Bibliographic Details
Main Authors: Benner, C. (Author), Duttke, S.H (Author), Glass, C.K (Author), Han, C.Z (Author), Hansen, A.H (Author), Hefzi, H. (Author), Karottki, K.J.L.C (Author), Kildegaard, H.F (Author), Lee, G.M (Author), Lewis, N.E (Author), Li, S. (Author), Roth, S.J (Author), Shamie, I. (Author), Tao, J. (Author), Xiong, K. (Author)
Format: Article
Language:English
Published: Oxford University Press 2021
Online Access:View Fulltext in Publisher