Computational analysis of sense-Antisense chimeric transcripts reveals their potential regulatory features and the landscape of expression in human cells

Computational analysis of sense-Antisense chimeric transcripts reveals their potential regulatory features and the landscape of expression in human cells

Many human genes are transcribed from both strands and produce sense-Antisense gene pairs. Sense-Antisense (SAS) chimeric transcripts are produced upon the coalescing of exons/introns from both sense and antisense transcripts of the same gene. SAS chimera was first reported in prostate cancer cells....

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Bibliographic Details
Main Authors: Balamurali, D. (Author), Detroja, R. (Author), Frenkel-Morgenstern, M. (Author), Gorohovski, A. (Author), Matveishina, E. (Author), Medvedeva, Y.A (Author), Mukherjee, S. (Author), Valencia, A. (Author)
Format: Article
Language:English
Published: Oxford University Press 2021
Subjects:
Article
atp6 protein
base pairing
breast cancer
cell adhesion molecule
chimera
cyclooxygenase 3
cytb protein
DNA hairpin
double stranded RNA
exon
gene
gene expression
gene mapping
gene ontology
gene sequence
gene structure
human
human cell
human tissue
long untranslated RNA
MCF-7 cell line
messenger RNA
Myc protein
nd2 protein
nd3 protein
nd4 protein
nd6 protein
palindromic DNA
protein
protein expression
protein kinase
protein p53
protein secondary structure
regulatory mechanism
RNA
RNA analysis
RNA directed RNA polymerase
RNA RNA hybridization
RNA sequencing
RNA splicing
sense antisense gene
small interfering RNA
small nuclear ribonucleoprotein
transcription regulation
transcriptome
ubiquitin protein ligase
unclassified drug
vasculotropin receptor
Watson Crick base pairing
zinc transporter
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