DNA methylation of OXTR is associated with parasympathetic nervous system activity and amygdala morphology

DNA methylation of OXTR is associated with parasympathetic nervous system activity and amygdala morphology

Oxytocin has anxiolytic properties whose mechanisms of action are still being identified. DNA methylation in the promoter region of the oxytocin receptor gene (OXTR), an epigenetic modification that putatively reflects a downtuning of the oxytocin system, has previously been implicated in the regula...

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Bibliographic Details
Main Authors: Connelly, J.J (Author), Goldbeck, L. (Author), Lancaster, K. (Author), Morris, J.P (Author), Puglia, M.H (Author)
Format: Article
Language:English
Published: Oxford University Press 2018
Subjects:
amygdala
Amygdala
anatomy and histology
anxiety
Anxiety
body mass
Body Mass Index
cholinergic system
DNA methylation
DNA Methylation
Epigenesis, Genetic
female
Female
genetic epigenesis
genetics
gray matter
Gray Matter
heart rate
Heart Rate
human
Humans
Magnetic Resonance Imaging
male
Male
neuroimaging
Neuroimaging
Neuroimaging epigenetics
nuclear magnetic resonance imaging
OXTR methylation
OXTR protein, human
oxytocin receptor
Parasympathetic nervous system
Parasympathetic Nervous System
physiology
Receptors, Oxytocin
young adult
Young Adult
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