Dynamical systems theory of cellular reprogramming

In cellular reprogramming, almost all epigenetic memories of differentiated cells are erased by the overexpression of a few genes, resulting in regaining pluripotency, the potential for differentiation. Considering the interplay between oscillatory gene expression and slower epigenetic modifications...

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Bibliographic Details
Main Authors: Hatakeyama, T.S (Author), Kaneko, K. (Author), Matsushita, Y. (Author)
Format: Article
Language:English
Published: American Physical Society 2022
Subjects:
Online Access:View Fulltext in Publisher