Dynamical systems theory of cellular reprogramming
In cellular reprogramming, almost all epigenetic memories of differentiated cells are erased by the overexpression of a few genes, resulting in regaining pluripotency, the potential for differentiation. Considering the interplay between oscillatory gene expression and slower epigenetic modifications...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Physical Society
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |