IPhantom: A Framework for Automated Creation of Individualized Computational Phantoms and Its Application to CT Organ Dosimetry

Objective: This study aims to develop and validate a novel framework, iPhantom, for automated creation of patient-specific phantoms or 'digital-twins (DT)' using patient medical images. The framework is applied to assess radiation dose to radiosensitive organs in CT imaging of individual p...

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Bibliographic Details
Main Authors:	Abadi, E. (Author), Fu, W. (Author), Iliopoulos, A.-S (Author), Lo, J.Y (Author), Samei, E. (Author), Segars, W.P (Author), Sharma, S. (Author), Sun, X. (Author), Wang, Q. (Author)
Format:	Article
Language:	English
Published:	Institute of Electrical and Electronics Engineers Inc. 2021
Subjects:	accuracy Article automation Automation Baseline methods bone breast calculation classification algorithm Clinical monitoring Clinical research comparative study computational human phantom Computational phantom Computational phantoms computer assisted tomography computer model Computerized tomography conceptual framework contour volume CT deformable registration Dice Similarity Coefficient diffeomorphic deformation diffeomorphic registration model Diffeomorphic registrations digital imaging and communications in medicine Digital twin dosimetry Dosimetry gallbladder geometry health care planning heart human Humans image quality image segmentation Image segmentation imaging phantom individualized computational phantom kidney large scale production Large-scale research learning based model Learning Based Models liver lung Markov chain Monte Carlo method Medical imaging multichannel large deformation diffeomorphic metric mapping normal distribution organ dose Phantoms Phantoms, Imaging photon transport preliminary data process optimization radiation dose radiation field Radiosensitive organs segmentation Similarity coefficients simulation soft tissue spleen statistical shape model thyroid gland Tomography, X-Ray Computed tube current modulation validation process x-ray computed tomography
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IPhantom: A Framework for Automated Creation of Individualized Computational Phantoms and Its Application to CT Organ Dosimetry

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