Prediction of Synthetic Lethal Interactions in Human Cancers Using Multi-View Graph Auto-Encoder
Synthetic lethality (SL) is a very important concept for the development of targeted anticancer drugs. However, experimental methods for SL detection often suffer from various issues like high cost and low consistency across cell lines. Hence, computational methods for predicting novel SLs have rece...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Institute of Electrical and Electronics Engineers Inc.
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |