Possible Contexts of Use for in Silico Trials Methodologies: A Consensus-Based Review

Possible Contexts of Use for in Silico Trials Methodologies: A Consensus-Based Review

The term 'In Silico Trial' indicates the use of computer modelling and simulation to evaluate the safety and efficacy of a medical product, whether a drug, a medical device, a diagnostic product or an advanced therapy medicinal product. Predictive models are positioned as new methodologies...

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Bibliographic Details
Main Authors: Afshari, P. (Author), Courcelles, E. (Author), Curreli, C. (Author), Emili, L. (Author), Famaey, N. (Author), Geris, L. (Author), Horner, M. (Author), Jori, M.C (Author), Kulesza, A. (Author), Loewe, A. (Author), Neidlin, M. (Author), Pappalardo, F. (Author), Reiterer, M. (Author), Rousseau, C.F (Author), Russo, G. (Author), Sonntag, S.J (Author), Viceconti, M. (Author), Voisin, E.M (Author)
Format: Article
Language:English
Published: Institute of Electrical and Electronics Engineers Inc. 2021
Subjects:
acute toxicity
animal experiment
Article
cancer stem cell
Cobalt alloys
Community of practice
computer model
Computer modelling and simulation
computer simulation
Computer Simulation
consensus
Consensus
Context of use
cryptosporidiosis
Diagnosis
drug safety
gene frequency
good simulation practice
human
Humans
In silico trials
in vitro study
machine learning
Medical Devices
Medical products
Medicinal products
micro-computed tomography
nonhuman
nuclear magnetic resonance imaging
personalized medicine
Predictive analytics
Predictive models
Regulatory assessment
Regulatory evaluation
signal transduction
simulation
sphingolipid
thrombectomy
thrombogenicity
validation process
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