GEFA: Early Fusion Approach in Drug-Target Affinity Prediction

Predicting the interaction between a compound and a target is crucial for rapid drug repurposing. Deep learning has been successfully applied in drug-target affinity (DTA)problem. However, previous deep learning-based methods ignore modeling the direct interactions between drug and protein residues....

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Bibliographic Details
Main Authors: Le, T.M (Author), Nguyen, T. (Author), Nguyen, T.M (Author), Tran, T. (Author)
Format: Article
Language:English
Published: Institute of Electrical and Electronics Engineers Inc. 2022
Subjects:
Online Access:View Fulltext in Publisher