Metformin in nucleus accumbens core reduces cue-induced cocaine seeking in male and female rats

This study investigated the potential therapeutic effects of the FDA-approved drug metformin on cue-induced reinstatement of cocaine seeking. Metformin (dimethyl-biguanide) is a first-line treatment for type II diabetes that, among other mechanisms, is involved in the activation of adenosine monopho...

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Bibliographic Details
Main Authors: Chan, A. (Author), Ibrahim, N. (Author), Mulloy, S. (Author), Schonfeld, M. (Author), Sciaccotta, A. (Author), Spencer, S.M (Author), Willard, A. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2022
Subjects:
Online Access:View Fulltext in Publisher