A batch-effect adjusted Simon's two-stage design for cancer vaccine clinical studies

In the development of cancer treatment vaccines, phase II clinical studies are conducted to examine the efficacy of a vaccine in order to screen out vaccines with minimal activity. Immune responses are commonly used as the primary endpoint for assessing vaccine efficacy. With respect to study design...

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Bibliographic Details
Main Authors: Bae, S. (Author), Huh, W.K (Author), Roden, R.B.S (Author), Rosner, G.L (Author), Wang, C. (Author), Wang, Z. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
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Online Access:View Fulltext in Publisher