Dose- and time-dependent effects of triethylene glycol dimethacrylate on the proteome of human THP-1 monocytes

Dose- and time-dependent effects of triethylene glycol dimethacrylate on the proteome of human THP-1 monocytes

Triethylene glycol dimethacrylate (TEGDMA) is commonly used in polymer resin-based dental materials. This study investigated the molecular mechanisms of TEGDMA toxicity by identifying its time- and dose-dependent effects on the proteome of human THP-1 monocytes. The effects of different concentratio...

Full description

Bibliographic Details
Main Authors: Bruun, J.-A (Author), Jensen, E. (Author), Michelsen, V.B (Author), Nilsen, B.W (Author), Örtengren, U. (Author), Simon-Santamaria, J. (Author), Sørensen, K.K (Author)
Format: Article
Language:English
Published: Blackwell Munksgaard 2018
Subjects:
cell culture technique
Cell Culture Techniques
cell cycle
Cell Cycle
cell proliferation
Cell Proliferation
cell survival
Cell Survival
Chromatography, Liquid
dental material
Dental Materials
DNA damage
DNA Damage
dose response
Dose-Response Relationship, Drug
drug effect
human
Humans
isotope labeling
liquid chromatography
macrogol
materials testing
Materials Testing
Mitochondria
mitochondrion
monocyte
Monocytes
oxidative stress
Oxidative Stress
Polyethylene Glycols
polymethacrylic acid derivative
Polymethacrylic Acids
proteome
Proteome
proteomics
reactive oxygen metabolite
reactive oxygen species
Reactive Oxygen Species
solvent
Solvents
tandem mass spectrometry
Tandem Mass Spectrometry
tandem mass spectroscopy
THP-1 cell line
THP-1 Cells
triethylene glycol dimethacrylate
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items