Effects of histone deacetylase inhibitors on regenerative cell responses in human dental pulp cells

Effects of histone deacetylase inhibitors on regenerative cell responses in human dental pulp cells

Aim: To investigate the growth, migratory and adhesive effects of trichostatin A (TSA) and valproic acid (VPA), two histone deacetylase inhibitors (HDACis), on human dental pulp stem cells (hDPSCs). Methodology: To verify that TSA or VPA functions as an HDAC inhibitor, the expressions of histones H3...

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Bibliographic Details
Main Authors: Cooper, P. (Author), Duncan, H. (Author), He, W. (Author), He, X. (Author), Liu, B. (Author), Liu, N. (Author), Luo, Z. (Author), Ma, F. (Author), Sun, L. (Author), Wang, J. (Author), Wang, Z. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Ltd 2018
Subjects:
adolescent
Adolescent
Blotting, Western
cell adhesion
Cell Adhesion
cell growth
cell migration
cell motion
Cell Movement
cell proliferation
Cell Proliferation
cytology
Dental Pulp
drug effect
histone
histone deacetylase
histone deacetylase inhibitor
histone deacetylase inhibitors
Histone Deacetylase Inhibitors
Histone Deacetylases
Histones
human
human dental pulp stem cells
Humans
hydroxamic acid
Hydroxamic Acids
metabolism
physiology
regeneration
Regeneration
stem cell
Stem Cells
tooth pulp
trichostatin A
valproic acid
Valproic Acid
Western blotting
young adult
Young Adult
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