Immune checkpoints indoleamine 2,3-dioxygenase 1 and programmed death-ligand 1 in oral mucosal dysplasia

Background: Oral mucosal dysplasia is a histologic feature of potentially malignant disorders that is associated with the risk of transformation to carcinoma. Dysplastic cells use many strategies during their transformation to cancer, including escape from the immune mediated destruction. We hypothe...

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Bibliographic Details
Main Authors:	Almahmoudi, R. (Author), Al-Samadi, A. (Author), Christopher, S. (Author), Passador-Santos, F. (Author), Salo, T. (Author), Sieviläinen, M. (Author), Siponen, M. (Author), Toppila-Salmi, S. (Author)
Format:	Article
Language:	English
Published:	Blackwell Publishing Ltd 2018
Subjects:	adaptive immunity Adaptive Immunity adult Adult alveolar mucosa Article B7-H1 Antigen CD274 protein, human cell infiltration controlled study disease exacerbation Disease Progression dysplasia female Female follow up Follow-Up Studies human human tissue Humans IDO1 immune checkpoint immunology indoleamine 2,3 dioxygenase indoleamine 2,3 dioxygenase 1 indoleamine 2,3-dioxygenase 1, human Indoleamine-Pyrrole 2,3,-Dioxygenase inflammation inflammatory cell lamina propria major clinical study male Male metabolism middle aged Middle Aged mouth disease Mouth Diseases mouth mucosa Mouth Mucosa mucosa oral biopsy oral dysplasia oral mucosal disease oral mucosal dysplasia pathology PD-L1 potentially malignant lesion priority journal programmed death 1 ligand 1 protein expression third molar time factor Time Factors tooth extraction unclassified drug young adult Young Adult
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Immune checkpoints indoleamine 2,3-dioxygenase 1 and programmed death-ligand 1 in oral mucosal dysplasia

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