Extracellular vesicle microRNA cargo is correlated with HPV status in oropharyngeal carcinoma

Extracellular vesicle microRNA cargo is correlated with HPV status in oropharyngeal carcinoma

Background: The incidence of human papilloma virus positive (HPV + ) oropharyngeal squamous cell carcinoma (OPSCC) has increased rapidly in recent decades. These tumours have a favourable outcome compared to HPV-negative (HPV − ) OPSCC. However, HPV + tumours are more likely to metastasise to distan...

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Bibliographic Details
Main Authors: Bradford, J. (Author), Hunt, S. (Author), Hunter, K. (Author), Lambert, D. (Author), Peacock, B. (Author), Pink, R. (Author), Rigby, A. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Ltd 2018
Subjects:
Article
bioinformatics
biological marker
Biomarkers, Tumor
CD63 antigen
CD9 antigen
cell communication
Cell Communication
Cell Line, Tumor
controlled study
exosome
extracellular vesicles
Extracellular Vesicles
genetics
head and neck cancer
human
human cell
human papillomavirus
Humans
isolation and purification
microRNA
MicroRNAs
nonhuman
oropharyngeal carcinoma
Oropharyngeal Neoplasms
oropharyngeal squamous cell carcinoma cell line
oropharynx carcinoma
oropharynx tumor
Papillomaviridae
papillomavirus infection
pathology
priority journal
RNA analysis
RNA sequence
tumor cell line
tumor marker
tumor susceptibility gene 101 protein
virology
Western blotting
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