Decreased Annexin A1 expression enhances sensitivity to docetaxel, cisplatin and 5-fluorouracil combination induction chemotherapy in oral squamous cell carcinoma

Decreased Annexin A1 expression enhances sensitivity to docetaxel, cisplatin and 5-fluorouracil combination induction chemotherapy in oral squamous cell carcinoma

Background: Annexin A1, a member of the Annexin superfamily, has been shown to play a vital role in a broad range of molecular and cellular processes. This study aims to explore the relationship between the Annexin A1 expression and the clinical response to cisplatin, docetaxel and 5-fluorouracil (T...

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Bibliographic Details
Main Authors: Aladelusi, T.O (Author), Ju, W. (Author), Sun, W. (Author), Zhang, Z. (Author), Zhao, T. (Author), Zhong, L. (Author), Zhu, D. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
Akt signaling
Annexin A1
antineoplastic agent
Antineoplastic Combined Chemotherapy Protocols
apoptosis
Article
biomarker
cancer radiotherapy
cancer staging
Carcinoma, Squamous Cell
caspase
cell proliferation
cell viability
chemotherapy
cisplatin
Cisplatin
controlled study
cytotoxicity
distant metastasis free survival
docetaxel
Docetaxel
down regulation
drug sensitivity
fluorouracil
Fluorouracil
follow up
genetic transfection
genetics
Head and Neck Neoplasms
head and neck tumor
human
human cell
human tissue
Humans
immunohistochemistry
in vitro study
induction chemotherapy
Induction Chemotherapy
lipocortin 1
major clinical study
Mouth Neoplasms
mouth squamous cell carcinoma
mouth tumor
oral squamous cell carcinoma
protein expression
protein kinase B
protein p27
squamous cell carcinoma
Squamous Cell Carcinoma of Head and Neck
taxoid
Taxoids
treatment outcome
upregulation
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