Effect of tyrosine kinase inhibitors on cell migration and epithelial-to-mesenchymal transition in Asian head and neck cancer cell lines

Effect of tyrosine kinase inhibitors on cell migration and epithelial-to-mesenchymal transition in Asian head and neck cancer cell lines

Background: We investigated the role of epidermal growth factor (EGF) and transforming growth factor α (TGFα) on Asian head and neck cancer patient cell lines; in terms of epithelial-to-mesenchymal transition (EMT) and cell migration to determine whether these changes could be reversed using tyrosin...

Full description

Bibliographic Details
Main Authors: Ellis, I.R (Author), Mossey, P. (Author), Thwe, A.M (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
Akt signaling
Article
Asian
Asian cell lines
cell line
Cell Line
Cell Line, Tumor
cell migration
cell motility
cell motion
Cell Movement
controlled study
down regulation
drug effect
EGFR signaling
epidermal growth factor
Epidermal Growth Factor
epidermal growth factor receptor
epithelial mesenchymal transition
epithelial-to-mesenchymal transition
erlotinib
gefitinib
HaCat cell line
head and neck cancer cell line
Head and Neck Neoplasms
head and neck tumor
HSG cell line
human
human cell
Humans
immunofluorescence
MAPK signaling
mitogen activated protein kinase
polyacrylamide gel electrophoresis
protein expression
protein function
protein kinase B
protein kinase inhibitor
Protein Kinase Inhibitors
protein phosphorylation
signal transduction
Signal Transduction
transforming growth factor alpha
tumor cell line
tyrosine
Western blotting
wound healing assay
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items