Anti-rheumatic medication and salivary MMP-8, a biomarker for periodontal disease

Anti-rheumatic medication and salivary MMP-8, a biomarker for periodontal disease

Objective: To investigate the impact of anti-rheumatic medications on salivary matrix metalloproteinase (MMP)-8 levels and MMP-8/TIMP (tissue inhibitor of MMPs)-1 ratio in patients with rheumatoid arthritis (RA) and periodontal findings during a 1-year follow-up. Materials and Methods: Salivary MMP-...

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Bibliographic Details
Main Authors: Ahola, K. (Author), Äyräväinen, L. (Author), Hämäläinen, M. (Author), Heikkinen, A.M (Author), Koivuniemi, R. (Author), Kuuliala, A. (Author), Leirisalo-Repo, M. (Author), Meurman, J.H (Author), Moilanen, E. (Author), Sorsa, T. (Author), Tervahartiala, T. (Author)
Format: Article
Language:English
Published: Blackwell Publishing Ltd 2018
Subjects:
adalimumab
adult
Adult
aged
Aged
anakinra
antirheumatic agent
Antirheumatic Agents
Arthritis, Rheumatoid
Article
biological marker
biological therapy
Biomarkers
bleeding on probing
certolizumab pegol
controlled study
corticosteroid therapy
DAS28
dental health
dental parameters
disease association
disease burden
disease duration
drug effect
enzyme linked immunosorbent assay
etanercept
female
Female
fluorometry
follow up
glucocorticoid
golimumab
human
Humans
hydroxychloroquine
immunoassay
immunofluorometric assay
leflunomide
low drug dose
major clinical study
male
Male
Matrix Metalloproteinase 8
matrix metalloproteinases
metabolism
methotrexate
middle aged
Middle Aged
neutrophil collagenase
nonsteroid antiinflammatory agent
periodontal disease
periodontal disease assessment
Periodontal Diseases
periodontal index
Periodontal Index
periodontal inflammatory burden index
periodontitis
pocket depth
prednisolone
priority journal
prospective study
rheumatoid arthritis
rituximab
salazosulfapyridine
saliva
Saliva
saliva analysis
saliva level
staging
TIMP1 protein, human
tissue inhibitor of metalloproteinase 1
Tissue Inhibitor of Metalloproteinase-1
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