An in vitro model for studies of attenuation of antibiotic-inhibited growth of Aggregatibacter actinomycetemcomitans Y4 by polyamines

An in vitro model for studies of attenuation of antibiotic-inhibited growth of Aggregatibacter actinomycetemcomitans Y4 by polyamines

Polyamines are ubiquitous polycationic molecules that are present in all prokaryotic and eukaryotic cells, and they serve as important modulators of cell growth, stress, and cell proliferation. Polyamines are present at high concentrations in the periodontal pocket and could potentially affect the s...

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Bibliographic Details
Main Authors: Dabdoub, S.M (Author), Ganesan, S.M (Author), Kumar, P.S (Author), Walters, J.D (Author), Wattimena, A. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
Aggregatibacter actinomycetemcomitans
amoxicillin
Anti-Bacterial Agents
antibiotic agent
antibiotic therapy
antiinfective agent
antimicrobial resistance
Article
azithromycin
bacterial growth
bacterial viability
bacterial virulence
biogenesis
brain
controlled study
doxycycline
growth inhibition
heart
in vitro study
metatranscriptomic analysis
microbial sensitivity test
Microbial Sensitivity Tests
minimum inhibitory concentration
nonhuman
periodontal pocket
physiological stress
polyamine
Polyamines
putrescine
scanning electron microscopy
spermidine
Spermidine
spermine
transcriptome
transcriptomics
upregulation
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