Clinical Metagenomic Sequencing for Species Identification and Antimicrobial Resistance Prediction in Orthopedic Device Infection

Clinical Metagenomic Sequencing for Species Identification and Antimicrobial Resistance Prediction in Orthopedic Device Infection

Diagnosis of orthopedic device-related infection is challenging, and causative pathogens may be difficult to culture. Metagenomic sequencing can diagnose infections without culture, but attempts to detect antimicrobial resistance (AMR) determinants using metagenomic data have been less successful. H...

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Bibliographic Details
Main Authors: Atkins, B.L (Author), Cregan, J. (Author), Crook, D.W (Author), Dudareva, M. (Author), Eyre, D.W (Author), Hoosdally, S. (Author), Jones, E. (Author), Kavanagh, J. (Author), Kolenda, C. (Author), McNally, M.A (Author), Oakley, S. (Author), O'Grady, J. (Author), Pickford, H. (Author), Sanderson, N.D (Author), Street, T.L (Author), Taunt, C. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Anti-Bacterial Agents
antibiotic resistance
antiinfective agent
antimicrobial resistance
Drug Resistance, Bacterial
high throughput sequencing
High-Throughput Nucleotide Sequencing
host depletion
human
Humans
metagenome
Metagenome
metagenomics
Metagenomics
orthopedic device infection
procedures
saponin
Saponins
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