Evaluation of the effects of library preparation procedure and sample characteristics on the accuracy of metagenomic profiles

Shotgun metagenomic sequencing has transformed our understanding of microbial community ecology. However, preparing metagenomic libraries for high-throughput DNA sequencing remains a costly, labor-intensive, and time-consuming procedure, which in turn limits the utility of metagenomes. Several libra...

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Bibliographic Details
Main Authors: Dasenko, M. (Author), Gaulke, C.A (Author), Schmeltzer, E.R (Author), Sharpton, T.J (Author), Thurber, R.V (Author), Tyler, B.M (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2021
Subjects:
Gut
Online Access:View Fulltext in Publisher