Metagenomic Sequencing Reveals that High-Grain Feeding Alters the Composition and Metabolism of Cecal Microbiota and Induces Cecal Mucosal Injury in Sheep

Metagenomic Sequencing Reveals that High-Grain Feeding Alters the Composition and Metabolism of Cecal Microbiota and Induces Cecal Mucosal Injury in Sheep

The cecum serves as an additional fermentation site for ruminants, but it lacks buffering capacity and has a relatively simple epithelial structure compared to the rumen. The role of high-grain (HG) diets in manipulating the rumen microbiome has been well elucidated, yet the microbial response to su...

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Bibliographic Details
Main Authors: Mao, S. (Author), Wang, Y. (Author), Xie, F. (Author), Xu, L. (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2021
Subjects:
acetyl coenzyme A
Akkermansia
Article
average daily gain
Blautia
Cecal microbiota
cecal mucosal injury
cecum
controlled study
Epithelial function
fermentation
gene expression
High-grain diet
hindgut
host microbe interaction
intestine flora
metabolism
metagenome
metagenomics
methanogenesis
microbial community
microbial diversity
Microbial perturbation
microbiome
Microbiome-host interactions
nonhuman
principal coordinate analysis
RNA 16S
Roseburia
Sheep
sheep disease
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