Genome-guided discovery of natural products through multiplexed low-coverage whole-genome sequencing of soil actinomycetes on Oxford Nanopore flongle

Genome mining is an important tool for discovery of new natural products; however, the number of publicly available genomes for natural product-rich microbes such as actinomycetes, relative to human pathogens with smaller genomes, is small. To obtain contiguous DNA assemblies and identify large (ca....

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Bibliographic Details
Main Authors: Bewley, C.A (Author), Liu, H.-B (Author), Ohlemacher, S.I (Author), Rajwani, R. (Author), Zhao, G. (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2021
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Online Access:View Fulltext in Publisher