Short-chain fatty acids reduced renal calcium oxalate stones by regulating the expression of intestinal oxalate transporter SLC26A6

Short-chain fatty acids reduced renal calcium oxalate stones by regulating the expression of intestinal oxalate transporter SLC26A6

Renal calcium oxalate (CaOx) stone is a common urologic disease with a high prevalence and recurrence rate. However, short-chain fatty acids (SCFAs) are less often reported in the prevention of urolithiasis. This study aimed to explore the effect of SCFAs on the renal CaOx stone formation and the un...

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Bibliographic Details
Main Authors: Jian, Z. (Author), Jin, X. (Author), Li, H. (Author), Liu, Y. (Author), Ma, Y. (Author), Qi, S. (Author), Sun, Q. (Author), Wang, K. (Author), Wei, Z. (Author), Xiang, L. (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2021
Subjects:
acetic acid
Adeno associated virus 9
adult
animal experiment
animal model
antibiotic agent
Article
butyric acid
Caco-2 cell line
calcium oxalate
calcium oxalate urolithiasis
cecum
controlled study
crystal structure
down regulation
drinking water
ethylene glycol
excretion
gene overexpression
Gut microbiota
human
in vitro study
in vivo study
Intestinal oxalate transporters
intestine flora
male
nonhuman
Oxalate
oxalate transporter slc26a3
oxalate transporter slc26a6
propionic acid
protein expression
rat
regulatory mechanism
Renal calcium oxalate stones
short chain fatty acid
Short-chain fatty acids
unclassified drug
upregulation
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