Collateral Sensitivity Interactions between Antibiotics Depend on Local Abiotic Conditions

Mutations conferring resistance to one antibiotic can increase (cross-resistance) or decrease (collateral sensitivity) resistance to others. Antibiotic combinations displaying collateral sensitivity could be used in treatments that slow resistance evolution. However, lab-to-clinic translation requir...

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Bibliographic Details
Main Authors: Allen, R.C (Author), Hall, A.R (Author), Pfrunder-Cardozo, K.R (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2021
Subjects:
Online Access:View Fulltext in Publisher