Proteomic profiling identifies Kaposi’s sarcoma-associated herpesvirus (KSHV)-encoded LANASIM-associated proteins in Hypoxia

Proteomic profiling identifies Kaposi’s sarcoma-associated herpesvirus (KSHV)-encoded LANASIM-associated proteins in Hypoxia

Hypoxia signaling is a key regulator in the development and progression of many types of human malignancies, including viral cancers. The latency-associated nuclear antigen (LANA), encoded by Kaposi’s sarcoma-associated herpesvirus (KSHV) during latency, is a multifunctional protein that plays an es...

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Bibliographic Details
Main Authors: Cai, Q. (Author), Du, S. (Author), Gan, J. (Author), Jia, Y. (Author), Liu, X. (Author), Qu, D. (Author), Robertson, E.S (Author), Wang, Y. (Author), Wei, F. (Author), Zhang, D. (Author), Zhu, C. (Author)
Format: Article
Language:English
Published: American Society for Microbiology 2021
Subjects:
Article
carcinogenesis
cell protein
coimmunoprecipitation
controlled study
cytoskeleton
DNA
DNA binding
gene silencing
HEK293 cell line
Herpesviridae
HNRNPU
human
human cell
HUVEC cell line
hypoxia
Hypoxia
KSHV
LANA
latency associated nuclear antigen
mass spectrometry
nonhuman
proteomics
RNA
RNA binding
SIM
SUMO-interacting motif
sumoylation
viral protein
wild type
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