PAX-D: study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression
INTRODUCTION: Clinical depression is usually treated in primary care with psychological therapies and antidepressant medication. However, when patients do not respond to at least two or more antidepressants within a depressive episode, they are considered to have treatment resistant depression (TRD)...
Main Authors: | Attenburrow, M.-J (Author), Au-Yeung, S.K (Author), Bogacz, R. (Author), Browning, M. (Author), Chan, F. (Author), Cipriani, A. (Author), Cleare, A. (Author), Cowen, P. (Author), Edwards, C. (Author), Evans, J. (Author), Geddes, J. (Author), Griffiths, J. (Author), Harmer, C.J (Author), Harrison, P.J (Author), Kessler, D. (Author), Lewis, G. (Author), Rendell, J. (Author), Roberts, S. (Author), Shanyinde, M. (Author), Simon, J. (Author), Singh, I. (Author), Watson, S. (Author), Yu, L.-M (Author) |
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Format: | Article |
Language: | English |
Published: |
NLM (Medline)
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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