Ultra-Highly Sensitive DNA Detection with Conducting Polymer-Modified Electrodes: Mechanism, Manufacture and Prospects for Rapid e-PCR

Ultra-Highly Sensitive DNA Detection with Conducting Polymer-Modified Electrodes: Mechanism, Manufacture and Prospects for Rapid e-PCR

At low copy number, sequence detection by polymerase chain reaction (PCR) requires up to 30 cycles (amplification 109) to produce a reliably detectable concentration of fluorescently-labelled amplicons. The cycle number and hence detection time is determined by the analytical sensitivity of the dete...

Full description

Bibliographic Details
Main Authors: Barker, D. (Author), Chan, E.W.C (Author), Evans, C.W (Author), Ghaus, Z.A (Author), Kerr-Philips, T. (Author), Travas-Sejdic, J. (Author), Williams, D.E (Author), Zhu, B. (Author)
Format: Article
Language:English
Published: IOP Publishing Ltd 2022
Subjects:
Amplicons
Charge transfer
Chemical detection
Conducting polymers
Copy number
Cycle number
Detection time
DNA
DNA detection
ELectrochemical detection
Electrode mechanism
Electrodes
Hybridisation
Oligonucleotides
Polymer films
Polymer modified electrodes
Polymerase chain reaction
Semiconducting films
Sequence detection
Solvents
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items