Acute toxicity and the effect of andrographolide on porphyromonas gingivalis -induced hyperlipidemia in rats

Acute toxicity and the effect of andrographolide on porphyromonas gingivalis -induced hyperlipidemia in rats

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The aim of the current study is to evaluate the effect of andrographolide on hyperlipidemia induced by Porphyromonas gingivalis in rats. Thirty male Sprague Dawley (SD) rats were divided into five groups as follows: group 1 (vehicle) and four experimental groups (groups 2, 3, 4, and 5) were challeng...

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Bibliographic Details
Main Authors: Abdulla, M.A (Author), Al Batran, R. (Author), Al-Bayaty, F. (Author), Al-Obaidi, M.M.J (Author)
Format: Article
Language:English
Subjects:
acute toxicity
andrographolide
animal
animal experiment
animal model
animal tissue
Animals
antioxidant
antioxidant activity
Antioxidants
article
bacterial cell
biological marker
Biological Markers
blood
carboxymethylcellulose
chemical analysis
cholesterol
cholesterol blood level
controlled study
diterpene
Diterpenes
drug effect
drug effects
enzyme blood level
fat droplet
female
glutathione peroxidase
Glutathione Peroxidase
high density lipoprotein
histopathology
hyperlipidemia
Hyperlipidemias
kidney
Kidney
lipid
lipid peroxidation
Lipid Peroxidation
Lipids
lipoprotein blood level
liver
Liver
low density lipoprotein
male
Male
malonaldehyde
Malondialdehyde
metabolism
microbiology
nonhuman
pathology
phosphate buffered saline
physiology
Porphyromonas gingivalis
rat
Rats
Rats, Sprague-Dawley
simvastatin
Sprague Dawley rat
superoxide dismutase
Superoxide Dismutase
toxicity
toxicity testing
Toxicity Tests, Acute
triacylglycerol
triacylglycerol blood level
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