Evaluation of the effect of andrographolide on atherosclerotic rabbits induced by Porphyromonas gingivalis

Evaluation of the effect of andrographolide on atherosclerotic rabbits induced by Porphyromonas gingivalis

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Epidemiologic evidence has demonstrated significant associations between atherosclerosis and Porphyromonas gingivalis (Pg). We had investigated the effect of andrographolide (AND) on atherosclerosis induced by Pg in rabbits. For experimental purpose, we separated thirty male white New Zealand rabbit...

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Bibliographic Details
Main Authors: Al Batran, R. (Author), Al-Bayaty, F. (Author), Hussain, S.F (Author), Jamil Al-Obaidi, M.M (Author), Mulok, T.Z (Author)
Format: Article
Language:English
Published: Hindawi Limited 2014
Subjects:
alpha smooth muscle actin
andrographolide
animal
animal experiment
animal model
animal tissue
Animals
antiatherogenic activity
Anticholesteremic Agents
antigen expression
antiinflammatory agent
Anti-Inflammatory Agents
Article
atherosclerosis
Atherosclerosis
atorvastatin
Bacteroidaceae infection
Bacteroidaceae Infections
blood
C reactive protein
CD36 antigen
comparative study
controlled study
C-Reactive Protein
cytokine
Cytokines
disease association
diterpene
Diterpenes
drug activity
drug effect
drug effects
drug megadose
experimental rabbit
female
Female
heptanoic acid derivative
Heptanoic Acids
high density lipoprotein
histopathology
hypocholesterolemic agent
immunohistochemistry
interleukin 1beta
interleukin 6
intima
investigative procedures
lipid
lipid analysis
Lipids
male
Male
maximum tolerated dose
metabolism
microbiology
morphometrics
Muscle, Smooth
nonhuman
Oryctolagus cuniculus
pathology
Porphyromonas gingivalis
pyrrole derivative
Pyrroles
rabbit
Rabbits
smooth muscle
Tunica Intima
Western blotting
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