Dengue patients exhibit higher levels of PrM and e antibodies than their asymptomatic counterparts

Dengue virus infection is a common tropical disease which often occurs without being detected. These asymptomatic cases provide information in relation to the manifestation of immunological aspects. In this study, we developed an ELISA method to compare neutralizing effects of dengue prM and E antib...

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Bibliographic Details
Main Authors:	Kumari Natkunam, S. (Author), Manikam, R. (Author), Ponnampalavanar, S. (Author), Rathakrishnan, A. (Author), Sathar, J. (Author), Sekaran, S.D (Author), Wang, S.M (Author), Yeo, A.S.L (Author)
Format:	Article
Language:	English
Published:	Hindawi Publishing Corporation 2015
Subjects:	Antibodies, Neutralizing Antibodies, Viral antigenicity Antigens, Viral Article Base Sequence blood sampling Blotting, Western controlled study dengue Dengue Dengue virus Dengue virus 1 Dengue virus 2 Dengue virus 3 Dengue virus 4 DNA sequence enzyme linked immunosorbent assay Enzyme-Linked Immunosorbent Assay Family Characteristics family size hemagglutination inhibition human Humans immunoglobulin M immunology M protein major clinical study molecular genetics Molecular Sequence Data neutralizing antibody nucleotide sequence polymerase chain reaction Polymerase Chain Reaction primary infection protein expression protein purification real time polymerase chain reaction recombinant envelope e protein recombinant protein Recombinant Proteins restriction mapping Restriction Mapping reverse transcription polymerase chain reaction secondary infection Sequence Analysis, DNA seroconversion serodiagnosis serotyping unclassified drug virology virus antibody virus antigen virus envelope protein Western blotting
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Dengue patients exhibit higher levels of PrM and e antibodies than their asymptomatic counterparts

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