Methanolic extract of clinacanthus nutans exerts antinociceptive activity via the opioid/nitric oxide-mediated, but cGMP-independent, pathways

Methanolic extract of clinacanthus nutans exerts antinociceptive activity via the opioid/nitric oxide-mediated, but cGMP-independent, pathways

Show other versions (1)

The objectives of the present study were to determine the mechanisms of antinociceptive effect of methanol extract of Clinacanthus nutans (Acanthaceae) leaves (MECN) using various animal nociceptive models. The antinociceptive activity of orally administered 10% DMSO, 100 mg/kg acetylsalicylic acid...

Full description

Bibliographic Details
Main Authors: Abdul Kadir, A. (Author), Abdul Rahim, M.H (Author), Ahmad, Z. (Author), Cheema, M.S (Author), Ching, S.M (Author), Mohd Sani, M.H (Author), Omar, M.H (Author), Yakob, Y. (Author), Zakaria, Z.A (Author)
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2016
Subjects:
Acanthaceae
adult
animal experiment
animal model
antinociception
antinociceptive agent
arginine
Article
Clinacanthus nutans
Clinacanthus nutans extract
controlled study
cyclic GMP
drug dose
hot plate test
male
nitric oxide
nitric oxide synthase
nociception
nonhuman
opiate
phytochemistry
plant extract
plant leaf
priority journal
rat
signal transduction
ultra performance liquid chromatography
unclassified drug
writhing test
Online Access:View Fulltext in Publisher
View in Scopus

Internet

View Fulltext in Publisher
View in Scopus

Similar Items