Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships between Therapeutic Action (Sub)classes

Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships between Therapeutic Action (Sub)classes

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Traditional Chinese medicine (TCM) still needs more scientific rationale to be proven for it to be accepted further in the West. We are now in the position to propose computational hypotheses for the mode-of-actions (MOAs) of 45 TCM therapeutic action (sub)classes from in silico target prediction al...

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Bibliographic Details
Main Authors: Bender, A. (Author), Drakakis, G. (Author), Fan, T.-P (Author), Fu, X. (Author), Liggi, S. (Author), Mohamad Zobir, S.Z (Author), Mohd Fauzi, F. (Author)
Format: Article
Language:English
Published: Hindawi Limited 2016
Subjects:
algorithm
Article
Chinese drug
Chinese medicine
computer model
digestive system
drug mechanism
drug targeting
G protein coupled receptor
gastrointestinal absorption
hypothesis
medical literature
non receptor protein tyrosine phosphatase 2
priority journal
protein kinase
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