Morphine Antidependence of Erythroxylum cuneatum (Miq.) Kurz in Neurotransmission Processes in Vitro

Morphine Antidependence of Erythroxylum cuneatum (Miq.) Kurz in Neurotransmission Processes in Vitro

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Opiate abuse has been studied to cause adaptive changes observed in the presynaptic release and the mediated-synaptic plasticity proteins. The involvement of neuronal SNARE proteins reveals the role of the neurotransmitter release in expressing the opioid actions. The present study was designed to d...

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Bibliographic Details
Main Authors: Adenan, M.I (Author), Amom, Z. (Author), Basir, R. (Author), Hidayat Baharuldin, M.T (Author), Mat Taib, C.N (Author), Mohd Moklas, M.A (Author), Suliman, N.A (Author)
Format: Article
Language:English
Published: Hindawi Limited 2016
Subjects:
alkaloid
alpha synuclein
Article
calcium cell level
calcium ion
calmodulin
cell lysate
controlled study
cytotoxicity
cytotoxicity test
dose response
down regulation
drug mechanism
Erythroxylum cuneatum
Erythroxylum cuneatum extract
human
human cell
IC50
in vitro study
medicinal plant
methadone
morphine
neurotransmission
plant extract
protein expression
synaptobrevin 2
synaptotagmin I
unclassified drug
upregulation
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