A Randomized Controlled Clinical Trial Exploring Safety and Tolerability of Sulthiame in Sleep Apnea

A Randomized Controlled Clinical Trial Exploring Safety and Tolerability of Sulthiame in Sleep Apnea

Rationale: Current therapies for obstructive sleep apnea (OSA) are limited by insufficient efficacy, compliance, or tolerability. An effective pharmacological treatment for OSA is warranted. Carbonic anhydrase inhibition has been shown to ameliorate OSA. Objectives: To explore safety and tolerabilit...

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Bibliographic Details
Main Authors: Grote, L. (Author), Hansen, C. (Author), Hedner, J. (Author), Hoff, E. (Author), Kuhn, K. (Author), Lennartz, P. (Author), Stenlof, K. (Author), Zou, D. (Author)
Format: Article
Language:English
Published: American Thoracic Society 2022
Subjects:
carbonic anhydrase inhibition
Continuous Positive Airway Pressure
controlled study
double blind procedure
Double-Blind Method
drug therapy
human
Humans
obstructive sleep apnea
pharmacology
positive end expiratory pressure ventilation
randomized controlled trial
RCT
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
sleep disordered breathing
sultiame
thiazine derivative
Thiazines
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