Integration of Murine and Human Studies for Mapping Periodontitis Susceptibility

Integration of Murine and Human Studies for Mapping Periodontitis Susceptibility

Periodontitis is one of the most common inflammatory human diseases with a strong genetic component. Due to the limited sample size of available periodontitis cohorts and the underlying trait heterogeneity, genome-wide association studies (GWASs) of chronic periodontitis (CP) have largely been unsuc...

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Bibliographic Details
Main Authors: Berger, K. (Author), Botzman, M. (Author), de Groot, L.C.P.G.M (Author), Divaris, K. (Author), Dommisch, H. (Author), Franke, A. (Author), Gat-Viks, I. (Author), Haddad, Y.H (Author), Hoffmann, P. (Author), Iraqi, F.A (Author), Kocher, T. (Author), Krone, B. (Author), Laudes, M. (Author), Lieb, W. (Author), Loos, B. (Author), Mott, R. (Author), Munz, M. (Author), Nashef, A. (Author), Offenbacher, S. (Author), Qabaja, R. (Author), Salaymeh, Y. (Author), Schaefer, A. (Author), Uitterlinden, A.G (Author), van der Velde, N. (Author), Wellmann, J. (Author), Wiess, E. (Author)
Format: Article
Language:English
Published: SAGE Publications Inc. 2018
Subjects:
alveolar bone loss
Alveolar Bone Loss
animal
animal model
Animals
chromosomal mapping
Chromosome Mapping
Collaborative Cross
diagnostic imaging
disease model
Disease Models, Animal
female
Female
genetic
Genetic Association Studies
genetic association study
genetic predisposition
Genetic Predisposition to Disease
genetics
genome-wide association study
Genome-Wide Association Study
GWAS
human
Humans
male
Male
Mice
micro-computed tomography
middle aged
Middle Aged
mouse
periodontitis
Periodontitis
QTL mapping
Quantitative Trait Loci
quantitative trait locus
X-Ray Microtomography
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