Multiple Functions of Lysyl Oxidase Like-2 in Oral Fibroproliferative Processes

Multiple Functions of Lysyl Oxidase Like-2 in Oral Fibroproliferative Processes

Gingival overgrowth is a side effect of certain medications, including calcium channel blockers, cyclosporin A, and phenytoin. Phenytoin-induced gingival overgrowth is fibrotic. Lysyl oxidases are extracellular enzymes that are required for biosynthetic cross-linking of collagens, and members of thi...

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Bibliographic Details
Main Authors: Findlay, A.D (Author), Kantarci, A. (Author), Mahjour, F. (Author), Mously, E.A (Author), Saxena, D. (Author), Trackman, P.C (Author)
Format: Article
Language:English
Published: SAGE Publications Inc. 2018
Subjects:
adult
Adult
Amino Acid Oxidoreductases
Blotting, Western
cell biology
cell culture
cell proliferation
Cell Proliferation
Cells, Cultured
collagen
Collagen
extracellular matrix
female
Female
fibroblast
fibroblasts
Fibroblasts
gene knockdown
Gene Knockdown Techniques
gingiva
Gingiva
growth, development and aging
human
Humans
LOXL2 protein, human
matrix biology
metabolism
oxidoreductase
physiology
platelet derived growth factor beta receptor
Receptor, Platelet-Derived Growth Factor beta
receptors
Western blotting
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