Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma

Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma

The accessibility of cell surface proteins makes them tractable for targeting by cancer immunotherapy, but identifying suitable targets remains challenging. Here we describe plasma membrane profiling of primary human myeloma cells to identify an unprecedented number of cell surface proteins of a pri...

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Main Authors: Anderson, G.S.F (Author), Anderson, K.C (Author), Asby, R. (Author), Aubareda, A. (Author), Ballester-Beltran, J. (Author), Bloxham, D. (Author), Chapman, M.A (Author), Ficken, C. (Author), Giotopoulos, G. (Author), Greaves, P. (Author), Guerrero, J.A (Author), Huntly, B.J.P (Author), Jenkinson, L. (Author), Keats, J.J (Author), Lehner, P.J (Author), MacFarlane, M. (Author), Nasser, S. (Author), Officer-Jones, L. (Author), Roy, J.P (Author), Skerget, S. (Author), So, T. (Author), Soilleux, E.J (Author), Surget, S. (Author), Tai, Y.-T (Author), Teodósio, A. (Author), Thaventhiran, J.E (Author), Walker, I. (Author), Williamson, J.C (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
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