Contact and intrinsic coagulation pathways are activated and associated with adverse clinical outcomes in COVID-19

Coagulation activation is a prominent feature of severe acute respiratory syndrome coronavirus 2 (COVID-19) infection. Activation of the contact system and intrinsic pathway has increasingly been implicated in the prothrombotic state observed in both sterile and infectious inflammatory conditions. W...

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Main Authors: Annichino-Bizzacchi, J.M (Author), Barbosa, M.S (Author), Bernardes, A.F (Author), Bombassaro, B. (Author), De Paula, E.V (Author), Dertkigil, S.S.J (Author), Henderson, M.W (Author), Huber, S.C (Author), Ilich, A. (Author), Key, N.S (Author), Lima, F. (Author), Mansour, E. (Author), Moraes, C.R.P (Author), Moretti, M.L (Author), Nunes, T.A (Author), Orsi, F.A (Author), Palma, A.C (Author), Ribeiro, L.C (Author), Santos, I. (Author), Strickland, S. (Author), Ulaf, R.G (Author), Velloso, L.A (Author)
Format: Article
Language:English
Published: American Society of Hematology 2022
Online Access:View Fulltext in Publisher