Infertile men older than 40 years are at higher risk of sperm DNA damage

Background: The effect of paternal age on semen quality is controversial. In this retrospective study, the aim was to investigate the effects of advancing age on sperm parameters including reactive oxygen species (ROS), total antioxidant capacity (TAC) and sperm DNA damage in infertile men. We also...

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Bibliographic Details
Main Authors:	Abuzenadah, A.M (Author), Agarwal, A. (Author), Alshahrani, S. (Author), Assidi, M. (Author), Ayaz, A. (Author), Durairajanayagam, D. (Author), Sabanegh, E. (Author), Sharma, R. (Author)
Format:	Article
Language:	English
Published:	BioMed Central Ltd. 2014
Subjects:	adult Adult age Age Factors Alcohol Drinking antioxidant Antioxidants chemoluminescence colorimetry complication controlled study DNA DNA damage DNA Damage DNA fragmentation drinking behavior genetics groups by age high risk patient human human cell human tissue Humans Infertility, Male major clinical study male Male male infertility Male infertility metabolism paternal age Paternal age procedures reactive oxygen metabolite Reactive Oxygen Species Retrospective Studies retrospective study Review risk assessment Risk Assessment risk factor Risk Factors semen analysis Semen Analysis Semen parameters smoking Smoking Sperm DNA damage Spermatozoa spermatozoon TUNEL assay varicocele Varicocele world health organization
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Infertile men older than 40 years are at higher risk of sperm DNA damage

Internet

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