Involvement of the TNF-α/SATB2 axis in the induced apoptosis and inhibited autophagy of osteoblasts by the antipsychotic Risperidone

Involvement of the TNF-α/SATB2 axis in the induced apoptosis and inhibited autophagy of osteoblasts by the antipsychotic Risperidone

Background: Risperidone, an atypical antipsychotic, impedes serotonin and dopamine receptor systems. Meanwhile, tumor necrosis factor-α (TNF-α) is known to participate in regulating osteoblast functions. Consequently, the current study aimed to investigate whether the influences of Risperidone on os...

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Bibliographic Details
Main Authors: Chen, M. (Author), Chen, Y. (Author), He, W. (Author), Huang, Y. (Author), Li, A. (Author), Miao, H. (Author), Xu, C. (Author), Zhang, Q. (Author), Zhang, S. (Author), Zhao, C. (Author), Zheng, D. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Apoptosis
Autophagy
Differentiation
Osteogenic differentiation
Risperidone
SATB2
Tumor necrosis factor-α
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