HapSolo: an optimization approach for removing secondary haplotigs during diploid genome assembly and scaffolding

Background: Despite marked recent improvements in long-read sequencing technology, the assembly of diploid genomes remains a difficult task. A major obstacle is distinguishing between alternative contigs that represent highly heterozygous regions. If primary and secondary contigs are not properly id...

Full description

Bibliographic Details
Main Authors: Gaut, B.S (Author), Long, A.D (Author), Solares, E.A (Author), Tao, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Online Access:View Fulltext in Publisher